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Klinische Studien – Teil 2. Daten kritisch bewerten können

C.C. Stülpnagel, M. Augustin, R. Sommer

Der Deutsche Dermatologe 2021; 69 (3): 36-42

 

Klinische Studien liefern eine Menge an Daten. Wie kommen sie zustande und wie sind sie zu interpretieren? Dieser Beitrag stellt die Grundlagen aus Epidemiologie und klinischer Forschung vor. Teil zwei folgt dann in der März-Ausgabe des "Deutschen Dermatologen" und informiert über wichtige Studienarten.

Skin Lesions, Skin Care, and Characteristics of Pruritus in Patients Undergoing Haemodialysis

R. Sommer1, S. Ständer2, M. Augustin1

1Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany

2Department of Dermatology and Center for Chronic Pruritus, University Hospital of Münster, Münster, Germany

Skin Pharmacol Physiol. 2021 Sep 14

 

Pruritus has been shown to be a common and burdensome complaint in the general population. In some diseases, there is an even higher rate and intensity of pruritus such as in chronic kidney diseases. In particular, patients re- quiring dialysis commonly suffer from pruritus with propor- tions between 22.0 and 90.0%. Few data on the characteris- tics and burden of such pruritus have been published. There- fore, the aim of this study was to investigate the extent and profiles of pruritus in such patients related to skin lesions and care.

PMID:
Epub ahead of print. 34521094
DOI:
10.1159/000519367

Klinische Studien – Teil 1. Daten und Ergebnisse besser verstehen

C.C. von Stülpnagel, M. Augustin, R. Sommer

Der Deutsche Dermatologe 2021; 69 (2): 122-127

 

Klinische Studien liefern eine Menge an Daten. Wie kommen sie zustande und wie sind sie zu interpretieren? Dieser Beitrag stellt die Grundlagen aus Epidemiologie und klinischer Forschung vor. Teil zwei folgt dann in der März-Ausgabe des "Deutschen Dermatologen" und informiert über wichtige Studienarten.

Stigma in visible skin diseases - a literature review and development of a conceptual model

N. Germain1, M. Augustin2, C. Francois1, K. Legau3, N. Bogoeva4, M. Desroches1, M. Toumi5, R. Sommer2

1HEOR, Creativ-Ceutical, Paris, France

2Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany

3LEO Pharma, Kopenhagen, Denmark

4HEOR, Creativ-Ceutical, Sofia, Bulgaria

5Public Health Department, Aix-Marseille University, Marseilles, France

J Eur Acad Dermatol Venereol. 2021 Jul;35(7):1493-1504

 

The burden of visible skin diseases (VSDs) includes not only physical symptoms but also psychosocial consequences such as depression, anxiety, impaired quality of life and low self-esteem. Stigmatization was shown to play a major role in people with skin diseases. The aim of the study was to review the evidence for the components, drivers and impacts of (self-)stigma, and to organize the data into a series of conceptual models.

PMID:
Epub 2021 Feb 12. 33428316
DOI:
10.1111/jdv.17110

Topologie der Psoriasis. Eine Prävalenzanalyse aus Real-World-Daten im Längs- und Querschnitt

C. Sorbe, R. Sommer, N. Kirsten, A. Danckworth, L.  Kühl, M. Augustin

Haut 2021; 32 (5): 212-214

Assessing the quality of life of people with chronic wounds by using the cross-culturally valid and revised Wound-QoL questionnaire

C.C. von Stülpnagel1, N. da Silva1, M. Augustin1, C. van Montfrans2, C. Fife3,4, A-M. Fagerdahl5, A. Gamus6, T. M. Klein1, C. Blome1, R. Sommer1

1German Center for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg- Eppendorf (UKE), Hamburg, Germany

2Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands

3Baylor College of Medicine, Houston, Texas 4The U.S. Wound Registry, Woodlands, Texas

5Department of Clinical Science and Education, Wound Centre, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

6Maccabi Health Services, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Wound Repair Regen. 2021 May;29(3):452-459

 

The Wound-QoL is an often used reliable and valid measure, originally developed in Germany. It has been sequentially translated and validated for other languages/coun- tries, for the measurement of health-related quality of life (HRQoL) in patients with chronic wounds. However, a study from the United States postulated its benefits from further adaptations. Furthermore, some patients struggled to provide an answer for some of the items. We aimed to test the cross-cultural structure and psychometric per- formance of the questionnaire to suggest necessary revisions.

PMID:
Epub 2021 Feb 17. 33595907
DOI:
10.1111/wrr.12901

Disease severity and patient needs/benefits in genital psoriasis: Patient-reported improvement after 6±1 months of Apremilast treatment

N. da Silva, R. Sommer, L. Mellars, C. von Stülpnagel, M. Cordey, M. Augustin (2021, November)

ePoster presented at 13th International Congress of Dermatology (ICD 2021) [Virtual].

Interpersonal experiences of stigmatization and sexual impairments, quality of life and depression in patients with psoriasis: The mediating role of social avoidance coping

N. da Silva, M. Augustin, D. Wilsmann-Theis, P. Staubach-Renz, C. von Stülpnagel (2021, September-October).

ePoster presented at 30th European Academy of Dermatology and Venereology (EADV) Congress [Virtual].

Disease burden and patient needs/benefits in patients with psoriasis with and without anogenital involvement: Preliminary results from the PsoGen study

N. da Silva, M. Augustin, D. Wilsmann-Theis, P. Staubach-Renz, C. von Stülpnagel (2021, September-October).

ePoster presented at 30th European Academy of Dermatology and Venereology (EADV) Congress [Virtual]

Bestimmung der transnationalen gesundheitsbezogenen Lebensqualität: Die kulturübergreifende Validität des überarbeiteten Wound-QoL-Fragebogens

C. von Stülpnagel, N. da Silva, M. Augustin, C. van Montfrans, C. Fife, AM. Fagerdahl, A. Gamus, TM. Klein, C. Bome, R. Sommer (2021, April). 

ePoster presented at 51. Jahrestagung der Deutschen Dermatologischen Gesellschaft (DDG-Tagung), Berlin, Germany. [Virtual].

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